Relationship between sleep duration, sun exposure, and serum 25-hydroxyvitamin D status: A cross-sectional study. Dietary sources and bioactivities of melatonin. Measuring light at night and melatonin levels in shift workers: A review of the literature. Effects of caffeine on sleep quality and daytime functioning. Blocking nocturnal blue light for insomnia: A randomized controlled trial. Shechter A, Kim EW, St-Onge MP, Westwood AJ. Melatonin for treatment-seeking alcohol use disorder patients with sleeping problems: A randomized clinical pilot trial. Gendy MNS, Lagzdins D, Schaman J, Le Foll B. Melatonin, the hormone of darkness: From sleep promotion to ebola treatment. Masters A, Pandi-Perumal SR, Seixas A, Girardin JL, McFarlane SI. Association of melatonin production with seasonal changes, low temperature, and immuno-responses in hamsters. Circadian rhythm disruption and mental health. Melatonin: Pharmacology, functions and therapeutic benefits. Taking melatonin with these drugs might increase the risk of seizures.Tordjman S, Chokron S, Delorme R, et al. Melatonin can stimulate immune function and interfere with immunosuppressive therapy.

This medication used to treat obsessive-compulsive disorder can increase melatonin levels, causing unwanted excessive drowsiness. Use melatonin cautiously if you take drugs such as diazepam (Valium, Valtoco, others) and others that are affected by these enzymes. Cytochrome P450 1A2 (CYP1A2) and cytochrome P450 2C19 (CPY2C19) substrates.Use of contraceptive drugs with melatonin might cause an additive sedative effect and increase possible side effects of melatonin. If you take diabetes medications, talk to your doctor before using melatonin. Melatonin use with these medications might cause an additive sedative effect. Central nervous system (CNS) depressants.Melatonin might worsen blood pressure in people taking blood pressure medications. Melatonin might inhibit the effects of anticonvulsants and increase the frequency of seizures particularly in children with neurological disabilities. Combining use of melatonin with them might increase the risk of bleeding. These types of drugs, herbs and supplements reduce blood clotting. Anticoagulants and anti-platelet drugs, herbs and supplements.Talk to your child's doctor before giving melatonin to a child. However, good bedtime habits are usually recommended as an initial treatment. Small studies have suggested melatonin might help treat sleep disturbances in children with a number of disabilities. It's not clear whether melatonin can improve daytime sleep quality and duration in people whose jobs require them to work outside the traditional morning to evening schedule. Evidence shows that melatonin can improve jet lag symptoms, such as alertness and daytime sleepiness. Melatonin might be more beneficial for older adults who could be melatonin deficient. Research suggests that melatonin might slightly reduce the time it takes to fall asleep, but its effects on sleep quality and total sleep time aren't clear. Research shows that melatonin reduces the length of time needed to fall asleep and advances the start of sleep in adults and children with this condition. In this disorder, your sleep pattern is delayed two hours or more from a conventional sleep pattern, causing you to go to sleep later and wake up later. Delayed sleep phase (delayed sleep-wake phase sleep disorder).Melatonin can help improve these disorders in adults and children. Circadian rhythm sleep disorders in the blind.

Research on melatonin use for specific conditions shows:

Naturvet quiet moments plus melatonin